Non-Clinical Toxicology Manager

This role is based in Barcelona, with an on-site commitment of three days a week. Fluency in English is required.

Join us at Alexion, AstraZeneca's Rare Disease division, as a Non-Clinical Manager. In this role, you will be a key component of the non-clinical team, working synergistically with the global project team, regulatory affairs and clinical team as the expert in early stages of drug development. This role may require working across projects and diseases

Your key accountabilities will be to support our programs, bringing your scientific and technical expertise to the teams to ensure the success of preclinical development programs. The right candidate will be a critical thinker that brings technical expertise and enthusiasm for the company along with a deep scientific knowledge. In collaboration with our partners (CROs), you will oversee the design, implementation, management and reporting of pre-clinical studies: pharmacokinetics, general toxicology, reproduction toxicology, genotoxicity, carcinogenicity, safety pharmacology.

In detail:

• Assist in selecting partners to conduct studies with regards to the expertise, quality, cost and time aspects.

• Act as the privileged contact with CROs for contracts, invoices, study setup, monitoring, onsite visit and reporting.

• Identify and resolve scientific, technical, logistical or quality issues related to studies.

• Ensure that studies comply with regulatory and quality requirements.

• Review, analyze and interpret the data, coordinate report review and finalization with highest quality standards.

• Summarize, communicate and promote results to the project teams and management.

• Coordinate activities with other departments (finances, CMC, bioanalysis, regulatory…).

• Closely monitor technological and regulatory developments in your field of expertise. ​

• PharmD, VetD, master’s degree in biology, animal sciences, toxicology or related fields.

• Minimum of 3-5 years of experience as a toxicology study director/monitor in pharma, biotech or CRO setting.

• Expertise in management of nonclinical studies, including the fundamentals of Good Laboratory Practices (GLP) and data interpretation of nonclinical studies.

• Ensure successful study execution within allocated budgets and timelines.

• Good interpersonal and communication skills with ability to relate to both internal and external stakeholders.

• Good organizational, planning, and project management skills, attention to detail.

• Good English proficiency (written and spoken), as it is a daily working.

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

Why AstraZeneca: Here, proximity to patients is real—we engage with individuals and families living with rare conditions to ensure our science serves their most pressing needs. You will experience the agility of a biotech environment backed by the reach, resources, and scientific depth of a global organization. We bring together diverse experts to solve complex problems quickly, valuing kindness alongside ambition, and empowering you to test ideas, learn fast, and see your impact in the advancement of first-in-class and best-in-class medicines.

Call to Action: If you are ready to turn nonclinical evidence into decisive progress for patients and help steer pioneering programs with clarity and speed, take the next step and join us to make your science count.

Date Posted

Closing Date

Alexion is proud to be an Equal Employment Opportunity and Affirmative Action employer. We are committed to fostering a culture of belonging where every single person can belong because of their uniqueness. The Company will not make decisions about employment, training, compensation, promotion, and other terms and conditions of employment based on race, color, religion, creed or lack thereof, sex, sexual orientation, age, ancestry, national origin, ethnicity, citizenship status, marital status, pregnancy, (including childbirth, breastfeeding, or related medical conditions), parental status (including adoption or surrogacy), military status, protected veteran status, disability, medical condition, gender identity or expression, genetic information, mental illness or other characteristics protected by law. Alexion provides reasonable accommodations to meet the needs of candidates and employees. To begin an interactive dialogue with Alexion regarding an accommodation, please contact accommodations@Alexion.com. Alexion participates in E-Verify.