Data Scientist, Biologics Engineering, Oncology R&D
Central to thisrolewill be the developmentof end-to-end data management and analysiscapabilities to delivernovelbiologicsdrugs driven by industry-leading biologics R&D data. Youwillbecome part of an interdisciplinaryBioinformatics team, working at the heartof research and developmentcreating an activelearning system, in whichmodelpredictions guide lab experiments, lab automation generateshigh-throughput data for modeltraining, and predictivemodelsareupdated as new data aregenerated.
ASTRAZENECA
Withoneof the broadest and deepestOncology pipelines in the industry, therearemanyopportunities to workwithnoveldrugs and helpdiscoverwhat'snext. We foster a mindsetofcourage, whereeveryone is empowered to step up, innovate and work at pace. Weleadthroughtruecollaboration, buildingcollectivewisdom by givingeveryone a chance to input. It's science with an impact-making a difference for patients and peoplearound the world.
SITE DESCRIPTION
The Gaithersburg site (https://www.youtube.com/watch?v=GOvxXGjBd1w) employs more than 3,500 experts in our field and is only a short drive from Washington, DC. Here, we play host to some of the most cutting-edge technology and lab spaces, all crafted to inspire collaboration and cross-functional science. We are dedicated to crafting a culture of collaboration. The Gaithersburg campus offers a variety of amenities to help boost efficiency and help keep our employees happy and healthy. This includes a fitness center, employee healthcare clinic, electric vehicle charging stations, dry cleaning, full-service cafeteria, game rooms, community garden and much more.
BUSINESS AREA
Join the Biologics Engineering team at AstraZeneca, where we are responsible for the discovery and optimisation of next-generation biological drug candidates across all key therapy areas. We are developing in-house biologics discovery platforms and novel drug modalities to address unmet medical needs. Be empowered to act fast on smart risks and keep ahead in the fast-paced Oncology field.
What you'll do
Youwillworkcloselywithour R&D scientists in fieldsof software engineering, lab automation, computationalmodelling and machinelearning, with access to biologics R&D data across AstraZeneca constantly generating new data to bothbuild and informpredictivemodels.Thisroleprovides the opportunity for a motivatedBioinformatician / Data Scientist to develop and manage the flowof data to create end-to-end data management capabilitiesthatwillhave a significantimpact on the deliveryof the novelbiologicsdrugsof the future.
Workwith scientists acrossBiologicsEngineering to develop end-to-end data management capabilities for biologicsdiscovery, creatingautomated pipelines for the flowof data.
Developapplications to configure and customizecommercialGenedataBiologics software for trackingbiologicsdiscovery data from antibody screening, protein engineering and protein production.
Extend the functionalityofGenedataBiologics by developingcustomcomputationaltoolsusingits Java Software Development Kit, for data ingestion from lab instruments and for data analysis.
Collaboratewith IT functionsresponsible for the deployment and maintenanceof the live GenedataBiologics system and its integration withexternaldatabases.
Collaboratewith web applicationdevelopers to integrate the GenedataBiologics system withcustomapplications for experiment design and data analysis.
Collaboratewithmachinelearningcolleagues to develop an activelearning system thatcontinuallytrainsmachinelearningmodels on data from biologics experiments and usesthese data to informsubsequent experiments.
Learnabout leading machinelearningmethods for biologics design and for activelearningapplied to biologics experiments.
Essential for the role
MS in computer science, bioinformatics or relevant computational field and 1+ year of experience OR BS and 3 years of experience
Experienceofworking in a scientificenvironment, generating insights from R&D data sets – preferablyDrug Discovery.
Experiencedevelopinghigh-qualityobjectoriented software in Java or Python.
Experiencewith software development best practices.
Experienceworkingwithin a team environment.
Can-do attitude. Actswithintegrity and does the right thing. Desire to learn and grow.
Desirable for the role
Experienceworking at interface ofdry / wet lab. Knowledgeof data formats for lab automation equipment.
Experiencewith SQL, includingconfiguring and queryingdatabasesprogrammatically.
ExperienceworkingwithGenedataBiologics or similarplatform for biological data management.
Demonstratedagilemethodologyfamiliarity.
Experiencedeveloping, debugging and data analysis pipelines and an understandingof the data requirements for downstreammachinelearning.
Exposure to graphdatabase systems and relatedquerylanguagese.g. SPARQL.
Why AstraZeneca?
We follow all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment.
Whenweputunexpected teams in the same room, weunleashboldthinkingwith the power to inspirelife-changingmedicines. In-person working gives us the platformweneed to connect, work at pace and challenge perceptions. That’swhywework, on average, a minimum ofthreedays per week from the office. Butthatdoesn'tmeanwe’re not flexible. Webalance the expectationofbeing in the officewhilerespectingindividualflexibility. Joinus in ourunique and ambitiousworld.
Competitive salary & benefits
Close date: 10/05/2024
So, what’s next!
Are you already imagining yourself joining our team? Good, because we can’t wait to hear from you. Don't delay, apply today!
Where can I find out more?
Our Social Media, Follow AstraZeneca on LinkedIn: https://www.linkedin.com/company/1603/
Inclusion & Diversity: https://careers.astrazeneca.com/inclusion-diversity
Career Site: https://careers.astrazeneca.com/
AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.
