Associate Director, Immuno-Imaging Scientist

Associate DirectorImmuno-Imaging scientist

Location: Waltham (US) 

Would you like to be part of a team that is at the leading edge of bioanalysis and spatial-omics technologies? Do you aspire to work in a world-leading, innovative and cross-functional environment? Are you looking to join a company that follows the science and turns ideas into life changing medicines? Then AstraZeneca might be the one for you!

We are seeking for a motivated and passionate individual to join us as an Associate Director, Immuno-Imaging scientist, in our Integrated Bioanalysis (IBA) organization within Clinical Pharmacology and safety sciences (CPSS). You will support biomarker discovery and validation, mechanistic studies as well as pharmacokinetic/toxicokinetic assessments for critical projects within AstraZeneca portfolio employing imaging and spatial biologytechnologies within the context of non-clinical and pre-clinical studies. You will work at the forefront of bioanalytical sciences and play a key role in the development and progression of new medicines to the market. We are looking for an enthusiastic and innovative team player with detailed knowledge of imaging for immunology and inflammation withdemonstrated hands-on experience. The position will be based at our vibrant strategic R&D site in Waltham (US) ahead of our move to Kendall Square Boston (US).

What you will do

As an Associate Director, Immuno-Imaging scientistin IBA at AstraZeneca, your main accountabilities will be to:

• Proficiency in advanced imaging techniques such as multiplexed immunofluorescence, spatial omics and multi-modal applications

• Support immunology portfolio with scientific leadership and focus on spatially resolved target characterization and immunophenotyping via advanced imaging technologies to inform safety, disease pathology and clinical translatability of biomarkers.

• Coordinate advanced image analysis support and data generation for portfolio supporting tissue-based imaging activities 

• Collaborate with cross functional teams e.g. Imaging scientists, Pathologists, In Vivo/Ex Vivo Bioscience, to develop bespokeimaging plans to support hypothesis driveninvestigations ordeep profiling for actionable insightfor drug safety and efficacy assessment.

• Communicates project results, conclusions and recommendations effectively to colleagues, project teams/stakeholders and collaborators through written reports and oral presentations at internal and external meetings.

• Contributes to the publication of scientific abstracts, posters, presentations, manuscripts and/or patent applications.

• Responsible for ensuring compliance with all AZ and site-specific policies, quality standards, SOPs, regulatory requirements, Safety Health & Environment (SHE) and Human and Animal Tissue standards (HBS)

Essential expertise needed:

• PhD in a Biological Scienceor related discipline with 5 or more years of related experience in academia or pharmaceutical/biotech/CRO organization

• Immunology Fundamentals: Strong understanding of immunological principles, including immune cell types, signalling pathways, and immune responses.

• Excellent organizational, documentation and technical writing skills 

• Excellent command of English (written and oral) 

• Strong communication and interpersonal skills 

• The ability to perform in a fast-paced, matrix-structured work environment. 

• Strong publication/presentation record in imaging sciences and/or immunology

• Knowledge of preclinical/clinical histopathology techniques such as H&E, IHC, multiplex IF & ISH is favourable. 

• Familiarity with the preclinical drug development process would be an advantage.

• Strong problem-solving skills with the ability to work both independently and collaboratively, and to handle several concurrent, fast-paced projects.
  

Desirable:

• Complementary bioanalytical technological experience 

• Integrated omics (data acquisition and analysis)

Why AstraZeneca?

At AstraZeneca when we see an opportunity for change, we seize it and make it happen, because any opportunity no matter how small, can be the start of something big. Delivering life-changing medicines is about being entrepreneurial -finding those moments and recognising their potential. Join us on our journey of building a new kind of organisation to reset expectations of what a bio-pharmaceutical company can be. This means we’re opening new ways to work, pioneering cutting edge methods and bringing unexpected teams together. Interested? Come and join our journey. 

So, What’s Next?

Are you already imagining yourself joining our team? Good, because we can’t wait to hear from you.