Associate Director, EUCAN International Health Economics and Outcomes Research

This is what you will do:

The Associate Director HEOR will be part of our EUCAN & International Team, and recently established Patient Reported Outcomes (PRO) Centre of Excellence (CoE).

The person we are looking for will support and guide countries on the development and execution of various HEOR projects of which the majority will be PRO and Quality of Life (QoL) related. The role consists of guiding and leading both global and country colleagues on HEOR and PRO strategies, study planning and implementation to support the upcoming reimbursement submissions of Alexion products. 

In this role the individual we are looking for will promote PRO & QoL expertise and give recommendations to the clinical development teams in close collaboration with our global HEOR indication leads. The position will be based in Barcelona, Spain.

Through key leadership and partnership across functional teams, the job holder also embeds global HEOR strategy into broader disease area and clinical development strategies. This collaboration builds strategies to demonstrate and differentiate the value proposition and corresponding scientific evidence of Alexion products for payers, patients, clinical institutions and other key stakeholders.

The HEOR Associate Director partners with and provides thought leadership to Market Access, Clinical Development and Commercial teams focusing on the specific PRO & QoL needs and requirements for for Alexion’s pipeline and inline products.

You will be responsible for:

The HEOR Associate Director will also be responsible in providing general HEOR input and guidance to countries.   

Utilizing in-depth knowledge of PRO & QoL with disease area and portfolio strategy in combination with HEOR expertise to develop and build capabilities for the PRO CoE.

Ensuring patient and stakeholder relevant PRO & QoL endpoints strategies are implemented throughout the product lifecycle.

In particular this Expert will support initiatives which incorporate the patient's perspective into clinical research and real-world evidence studies. Including designing, developing, and implementing PRO & QoL measures to assess the impact of diseases and treatments on patient well-being.

Accountable for the following:

• Building collaborative relationships with cross-functional leaders across Medical, Research & Development, Commercial, Market Access organizations to maximize PRO & QoL and HEOR efforts to optimize launch and sustained reimbursement throughout the product lifecycle
• Partnering with the Head of the PRO Center of Excellence and Regional/Country market access and medical teams to develop HEOR and PRO strategies that will provide a competitive advantage to differentiated patient relevant evidence.
• Developnig and validating, as needed, PRO instruments to capture patient experiences and outcomes effectively.
• Analyzing and interpreting PRO data to provide insights into patient-centric outcomes and inform decision-making, including HTA processes.
• Developing and establishing, as needed, Minimal Clinically Important Differences (MCID) for patient-reported outcome measures to interpret the significance of observed changes in clinical trials.
• Providing expert guidance or conduct psychometric analyses to assess and ensure the reliability, validity, and responsiveness of PRO measures.
• Providing subject-matter expertise and training on PROs to internal teams and stakeholders.
• Preparing and presenting findings to internal stakeholders, external agencies, and scientific audiences.

You will need to have:

• PhD, MSc in health economics, outcomes research or equivalent combination of education and experience
• 7+ years prior experience in HEOR with extensive PRO & QoL knowledge in the biopharmaceutical/pharmaceutical or consulting industry
• Strong Expertise and hands on experience in PRO development and implementation in clinical trials as well as from observational studies.   
• Experience with and good understanding of cost effectiveness and budget impact modeling.
• Experience in RWE, both prospective and retrospective observational research.     
• Knowledge of the field of Health Technology Assessment at a global level and experience of negotiations through the HTA processes
• Understanding of the global international market access landscape
• Knowledge of the drug development and commercialization process within pharma
• Recognized as a strong leader with a proven track record of effectively managing, influencing and developing people including those who are not direct reports: demonstrated ability to lead and deliver results in a matrix environment, and solve complex issues that cross multiple stakeholders
• Excellent interpersonal skills with a track record of effectiveness as a team player; excellent oral/written communication and presentation skills
• Excellent project leader who can effectively manage multiple competing priorities to completion
• Flexibility and adaptability to internal and external change
• Fluent in English spoken and written
• The duties of this role are generally conducted in an office environment. As is typical of an office-based role, employees must be able, with or without an accommodation to: use a computer; engage in communications via phone, video, and electronic messaging; engage in problem solving and non-linear thought, analysis, and dialogue; collaborate with others; maintain general availability during standard business hours.

We would prefer for you to have:

• Experience and knowledge in rare disease conditions
• Proficiency in additional languages beyond English

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.