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Proteomics Scientist, Chemical Biology Group

Местоположение Уолтем, Массачусетс, США Идентификатор вакансии R-066299 Дата публикации 11/19/2019

Proteomics Scientist, Chemical Biology Group

At AstraZeneca, we work together across global boundaries to discover, develop, manufacture and market prescription medicines that make a positive impact on the lives of patients as well as their families and communities.  At AstraZeneca, our vision is redefining cancer, redefining our solutions to cancer and restoring patients' lives.  Our mission is to make a meaningful difference to patient health through great medicines that bring benefit for patients and add value for society.

In addition to our passion for the discovery of innovative new medicines, we understand the importance of flexibility in our work-life environment and we offer a wide variety of benefits, services and programs that provide our employees the resources they need to pursue not only their work goals but also their life goals.  We are dedicated to building strong research teams that embrace the diversity of talents of team members and allow the larger group to grow and learn together to accomplish our collective goal to improve human health.

As a Proteomics Scientist, you will be working in our Chemical Biology and Proteomics group to perform sample preparation and LC/MS based quantitative proteomics.  These experiments will answer important scientific questions for the AstraZeneca drug projects.  You must be highly detailed oriented, organized, and able to work on complex problems. Hands-on experience with LC-MS/MS of proteins and peptides and experience in proteomics sample preparation for mass spectrometry are a plus, but not required.

Responsibilities for position include:

  • Preparation of samples from cells and tissues to support proteomics studies including protein digestion, isobaric tagging and peptide purification.
  • Operation and maintaining multiple mass spectrometers as well as troubleshooting of state-of-the art Orbitrap mass spectrometers and nanoLC systems
  • Analysis and interpretation of proteomics study results to collaborating scientists.
  • Attending and participate in meetings for setting mass spectrometry operational priorities.
  • Ability to work independently but also to succeed in a multidisciplinary team environment.

Additional desirable skills and experience:  characteristics and qualifications:

  • Experience in conducting method development for HPLC and/or mass spectrometry.
  • Knowledge of statistics, proteomics bioinformatics software, and mass spectrometry database search algorithms.
  • Have desire to develop or evaluate innovative and relevant MS-based proteomics technologies.
  • Good communication skills, both written and verbal, and organizational skills.
  • Experience with liquid handling automation for proteomic sample preparation a plus.


  • BS or MS degree in biochemistry, chemistry or biological science with 2+ years or relevant experience. 

Next Steps – Apply today!

  • AstraZeneca is a global, innovation-driven biopharmaceutical business that focuses on the discovery, development and commercialization of prescription medicines for some of the world’s most serious diseases. But we're more than one of the world's leading pharmaceutical companies. At AstraZeneca, we're proud to have a unique workplace culture that inspires innovation and collaboration. Here, employees are empowered to express diverse perspectives - and are made to feel valued, energized and rewarded for their ideas and creativity.
  • To be considered for this exciting opportunity, please complete the full application on our website at your earliest convenience – it is the only way that our Recruiter and Hiring Manager can know that you feel well qualified for this opportunity.  If you know someone who would be a great fit, please share this posting with them.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.

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